CORMs protect endothelial cells during cold preservation, resulting in inhibition of intimal hyperplasia after aorta transplantation in rats
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چکیده
منابع مشابه
Effect of Anastomotic Method on Intimal Hyperplasia in Rabbit Aorta
Purpose: The clinical advantages of end-to-end (ETE) anastomosis have not been clear despite its biomechanical advantage over end-to-side (ETS) anastomosis. We compared the histomorphometric features of intimal remodeling after ETE and ETS anastomosis in a rabbit aortic bypass model. Methods: Thirty-two bypass operations, 16 with ETS and 16 with ETE anastomoses, were performed using aortic allo...
متن کاملEndothelial implants inhibit intimal hyperplasia after porcine angioplasty.
The perivascular implantation of tissue-engineered endothelial cells around injured arteries offers an opportunity to study fundamental vascular physiology as well as restore and improve tissue function. Cell source is an important issue because the ability to implant either xenogeneic or allogeneic cells would greatly enhance the clinical applications of tissue-engineered grafts. We investigat...
متن کاملLate-outgrowth endothelial cells attenuate intimal hyperplasia contributed by mesenchymal stem cells after vascular injury.
OBJECTIVE Mesenchymal stem cells (MSCs) are one of a number of cell types undergoing extensive investigation for cardiac regeneration therapy. It has not yet been determined whether this cell therapy also substantially contributes to vascular remodeling of diseased vessels. METHODS AND RESULTS Human MSCs and a variety of progenitor and vascular cells were used for in vitro and in vivo experim...
متن کاملInhibition of MiR-92a May Protect Endothelial Cells After Acute Myocardial Infarction in Rats: Role of KLF2/4
BACKGROUND This study was designed to investigate the effects of microRNA-92 (miR-92), Kruppel-like factor 2 (KLF2), and Kruppel-like factor 4 (KLF4) on endothelial injury after acute myocardial infarction (AMI). MATERIAL AND METHODS Blood samples were collected from 50 AMI patients for detection of cardiac troponin I (cTnI), heart-type fatty acid-binding protein (H-FABP), and von Willebrand fa...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2010
ISSN: 0934-0874
DOI: 10.1111/j.1432-2277.2010.01102.x